Aborted donor hepatectomy in living donor liver transplantation: lessons learned

Keywords: living donor liver transplantation, living donor hepatectomy, aborted donor hepatectomy, no-go donor hepatectomy, beginning syndrome

Abstract

Background: Aborted donor hepatectomy (ADH) during any stage of living donor hepatectomy (LDH) is a rare event. We describe our experience and discuss the lessons from these events.

Methods: From September 2005 to January 2019, 77 of 2 031 (3.79%) LDH were aborted at various stages of surgical procedure due to donor or recipient related reasons. Demographic and clinical data of aborted donor candidates and the clinical course of their potential recipients were analysed.

Results: LDH of 77 donor candidates was aborted due to donor (n = 53) or recipient (n = 24) related reasons. The most common donor related reason was the quality of liver parenchyma (n = 31). The most common recipient related reason was haemodynamic instability (n = 11). Twenty-three recipients underwent either living donor liver transplantation (LDLT) (n = 21) or deceased donor liver transplantation (DDLT) (n = 2) at a median of 6 days following ADH. In one aborted due to a donor reason and two aborted for recipient reasons, LDLT was performed using the same donor candidates. Thirty-six recipients had no liver transplantation (LT) and died a median of 17.5 days following ADH.

Conclusions: We believe that ADH will decrease with experience and meticulous preoperative clinical and radiological evaluations. Abandoning the donor hepatectomy is always a valid option at any stage of the surgery when the unexpected is encountered.

Author Biographies

K Kutluturk, Inonu University

Liver Transplant Institute, Inonu University Faculty of Medicine, Turkey

S Akbulut, Inonu University

Liver Transplant Institute, Inonu University Faculty of Medicine, Turkey

A Baskiran, Inonu University

Liver Transplant Institute, Inonu University Faculty of Medicine, Turkey

F Gonultas, Inonu University

Liver Transplant Institute, Inonu University Faculty of Medicine, Turkey

A Dirican, Inonu University

Liver Transplant Institute, Inonu University Faculty of Medicine, Turkey

B Isik, Inonu University

Liver Transplant Institute, Inonu University Faculty of Medicine, Turkey

S Yilmaz, Inonu University

Liver Transplant Institute, Inonu University Faculty of Medicine, Turkey

Published
2020-06-29
How to Cite
Kutluturk, K., Akbulut, S., Baskiran, A., Gonultas, F., Dirican, A., Isik, B., & Yilmaz, S. (2020). Aborted donor hepatectomy in living donor liver transplantation: lessons learned. South African Journal of Surgery, 58(02), 91-100. Retrieved from http://sajs.redbricklibrary.com/index.php/sajs/article/view/3143
Section
Transplantation