The role of surgery in an imatinib-resistant GIST liver secondary

Emil Loots

doi:10.7196/sajsnew.7861

The role of surgery in an imatinib-resistant GIST liver secondary

Emil Loots Department of General Surgery, Inkosi Albert Luthuli Central Hospital; and Department of General Surgery, University of KwaZulu-Natal, Durban

DOI: https://doi.org/10.7196/sajsnew.7861

Keywords: Stomach GIST, Liver metastasis, Exon mutation

Abstract

This is a case report describing the management of an imatinib-resistant liver secondary as a result of an exon 13 mutation. The gastric primary was completely excised 3 years prior and proven to contain an exon 11 mutation. Resective liver surgery was undertaken after the patient developed imatinib resistance and he has been disease-free for 19 months. The application of surgery in the context of other treatment options is discussed.

Author Biography

Emil Loots, Department of General Surgery, Inkosi Albert Luthuli Central Hospital; and Department of General Surgery, University of KwaZulu-Natal, Durban

FCS (SA), Cert Gastro (SA) Surg

Figure 1

Published

2015-09-25

How to Cite

Loots, E. (2015). The role of surgery in an imatinib-resistant GIST liver secondary. South African Journal of Surgery, 53(2), 70-71. https://doi.org/10.7196/sajsnew.7861

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Issue

Vol 53 No 2 (2015)

Section

Case Reports

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