Ten-year survival of patients with oesophageal squamous cell carcinoma

  • Wei Hu Department of Thoracic Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou
  • Yayong Liang Department of Pediatrics, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou
  • Shuishen Zhang Department of Thoracic Oncology, Cancer Centre, Sun Yat-sen University, Guangzhou
  • Yi Hu Department of Thoracic Oncology, Cancer Centre, Sun Yat-sen University, Guangzhou
  • Jingeng Liu Department of Thoracic Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou
Keywords: Esophageal squamous cell carcinoma, Esophagectomy, Prognosis

Abstract

Objectives. The standard predictive factors of actuarial survival such as T and N stage become less important as patients live for more than 10 years after treatment of cancer. Reports of actual 10-year survivors of oesophageal squamous cell carcinoma (SCC) are rare, and demographic and clinicopathological factors associated with 10-year survival have not been well documented. In this research we evaluated factors predictive of actual, as opposed to actuarial, 10-year survival. Methods. We retrospectively analysed 1 046 patients who had undergone oesophagectomy for oesophageal SCC. The demographic and clinicopathological characteristics of patients who were alive more than 10 years after oesophagectomy and those of patients who had died were compared. Results. Univariate analysis showed that 18 factors differed significantly between the two groups. Based on logistic regression analysis, factors associated with 10-year survival were younger age, female gender, absence of dysphagia, a left transthoracic surgical approach, lower pathological T stage, and fewer metastatic lymph nodes. Conclusion. The independent positive predictors of actual as opposed to actuarial 10-year survival are younger age, female gender, absence of dysphagia, lower pathological T stage, and fewer metastatic lymph nodes.
Published
2013-05-03
How to Cite
Hu, W., Liang, Y., Zhang, S., Hu, Y., & Liu, J. (2013). Ten-year survival of patients with oesophageal squamous cell carcinoma. South African Journal of Surgery, 51(2), 62-66. https://doi.org/10.7196/sajs.1453
Section
General Surgery